Azithromycin 500 mg is an antibiotic used to treat various bacterial infections, but it's not typically the first choice for a sore throat. Most sore throats are caused by viral infections, like the common cold, and antibiotics like azithromycin are ineffective against viruses.

However, if a sore throat is due to a bacterial infection, such as strep throat, azithromycin might be prescribed if you're allergic to penicillin or if other antibiotics are unsuitable. Azithromycin works by inhibiting bacterial protein synthesis, thereby stopping the growth of bacteria.

For viral sore throats, treatments usually focus on relieving symptoms rather than using antibiotics. This includes staying hydrated, using throat lozenges, and taking over-the-counter pain relievers.

Always consult a healthcare provider for an accurate diagnosis and appropriate treatment. Misuse of antibiotics can lead to resistance and other complications.